Ryan Reynolds, ‘Two Guys, a Girl and a Pizza Place’ (1998-2001)

Ryan Reynolds as a mischievous prankster? Naw, we can’t buy that. The future Deadpool starred in this ABC sitcom (later shortened to just “Two Guys and a Girl”) for 4 seasons, until it was given the Friday night death slot. Nathan Fillion joined the show in the second season. His next TV gigs: “Firefly” and “Castle.” So that worked out okay.

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